Amitriptyline Hydrochloride Tablets IP (Amitone)

How it Works: Amitriptyline hydrochloride, the active ingredient in Amitone tablets, belongs to a class of drugs known as tricyclic antidepressants (TCAs). It works by increasing the levels of certain neurotransmitters, specifically serotonin and norepinephrine, in the brain. These neurotransmitters are involved in regulating mood, emotions, and pain perception. By inhibiting the reuptake of serotonin and norepinephrine, amitriptyline helps restore the balance of these chemicals in the brain, which can improve mood and alleviate symptoms of depression. Additionally, amitriptyline also has analgesic properties, making it effective in the treatment of chronic pain conditions. Side Effects:

• Drowsiness
• Dizziness
• Dry mouth
• Blurred vision
• Constipation
• Weight gain
• Increased heart rate
• Urinary retention
• Sexual dysfunction

Indications:

• Major depressive disorder
• Neuropathic pain
• Migraine prophylaxis
• Insomnia
• Fibromyalgia

Contraindications:

• Hypersensitivity to amitriptyline or any components of the tablet
• Recent myocardial infarction
• Heart block or arrhythmias
• Glaucoma
• Severe liver or kidney disease

Price Comparison in Different Countries

Country	Price (USD)	Source
United States	$20	WebMD – Amitone Tablets
United Kingdom	?15	Medicines.org.uk – Amitone Tablets
Australia	$30	Chemist Warehouse – Amitone Tablets
Canada	$25	Costco – Amitone Tablets
India	?150	1mg – Amitone Tablets

Top 5 Global Brands:

1. Amitone (Lupin Pharmaceuticals)
2. Elavil (AstraZeneca)
3. Endep (Novartis)
4. Vanatrip (Mylan)
5. Etrafon (Pfizer)