Benepali 50 mg solution for injection in pre-filled pen
Condition : New
0
From UAE
To United States
in 5-10 days
Description
Benepali is a biosimilar to Enbrel (etanercept), used to treat autoimmune diseases by interfering with tumor necrosis factor (TNF), a soluble inflammatory cytokine. Each pre-filled pen contains 50 mg of etanercept, designed for subcutaneous administration. Benepali is used in various inflammatory conditions, particularly in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis.
How It Works
Benepali works by binding to and inhibiting TNF-alpha, a pro-inflammatory cytokine involved in the inflammatory processes of autoimmune diseases. TNF-alpha is produced by cells of the immune system and contributes to inflammation and joint damage in rheumatoid arthritis and other conditions. By blocking the activity of TNF-alpha, Benepali reduces inflammation, alleviates symptoms, and prevents disease progression.Indications
- Rheumatoid arthritis (moderate to severe) in adults
- Psoriatic arthritis
- Ankylosing spondylitis
- Non-radiographic axial spondyloarthritis
- Plaque psoriasis in adults and children
- Juvenile idiopathic arthritis
Contraindications
- Known hypersensitivity to etanercept or any of the excipients
- Sepsis or risk of sepsis
- Active infections, including chronic or localized infections
Side Effects
- Injection site reactions (redness, itching, swelling)
- Infections (upper respiratory tract infections, sinusitis)
- Headache
- Nausea
- Rash
- Abdominal pain
- Allergic reactions
- Serious infections (pneumonia, tuberculosis)
- Blood disorders (anemia, leukopenia)
- Heart failure
- Autoimmune disorders (lupus-like syndrome)
Price in Different Countries
Country | Price (per pre-filled pen) | References |
---|---|---|
United States | $2,000 | GoodRx Benepali Price |
United Kingdom | £1,600 | NHS Benepali Price |
Canada | $1,800 | Canada Drugs Benepali Price |
Australia | $1,900 | PBS Benepali Price |
India | ₹140,000 | 1mg Benepali Price |
Top 5 Global Brands
- Benepali (Samsung Bioepis/Biogen): A biosimilar to Enbrel, used to treat various autoimmune diseases.
- Enbrel (Amgen/Pfizer): The original brand of etanercept, widely used for treating rheumatoid arthritis and other inflammatory conditions.
- Humira (AbbVie): A monoclonal antibody targeting TNF-alpha, used for treating rheumatoid arthritis, Crohn’s disease, and other autoimmune diseases.
- Remicade (Janssen Biotech): An anti-TNF monoclonal antibody used for treating autoimmune diseases such as rheumatoid arthritis and Crohn’s disease.
- Simponi (Janssen Biotech): Another anti-TNF agent used for treating various inflammatory conditions, including rheumatoid arthritis and ulcerative colitis.