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  • Bimzelx (bimekizumab-bkzx)

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    Description

    Bimzelx (bimekizumab) is a monoclonal antibody used for treating moderate to severe plaque psoriasis in adults. It works by selectively binding and neutralizing interleukin-17A and interleukin-17F (IL-17A and IL-17F), which are cytokines involved in inflammatory processes.

    Mechanism of Action:

    Bimzelx blocks the activity of IL-17A and IL-17F cytokines, preventing them from interacting with their receptors, which are crucial in driving inflammation in skin conditions like psoriasis.

    Indications:

    Bimzelx is primarily indicated for:
    • Moderate to severe plaque psoriasis in adults, especially when other systemic therapies are inadequate.

    Side Effects:

    Common side effects of Bimzelx include:
    • Upper respiratory infections
    • Oral candidiasis (fungal infection in the mouth)
    • Injection site reactions
    • Headache
    • Herpes simplex infections
    • Gastroenteritis
    • Tinea infections (fungal)

    Contraindications:

    Bimzelx should not be used in the following conditions:
    • Active infections: Patients with untreated tuberculosis or other serious infections should avoid this treatment.
    • Hypersensitivity: Anyone with known allergies to bimekizumab or its excipients.
    • Severe depression or suicidal ideation: Use with caution in patients with a history of depression

    Global Prices:

    Bimzelx (Bimekizumab) Prices in Different Countries

    Country Price (per injection) Source
    USA $13,000 Drugs.com
    UK £9,500 NHS
    Germany €12,000 MIMS Germany
    Canada CAD 16,000 Health Canada
    Australia AUD 18,000 PBS Australia
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    Bimzelx (bimekizumab-bkzx)
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