Bosulif (bosutinib) 500mg Tablet


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How it Works: Bosulif inhibits the activity of specific proteins known as tyrosine kinases. These proteins are involved in the signaling pathways that control cell growth and division. In chronic myeloid leukemia (CML), there is a genetic mutation that leads to the overactivation of a tyrosine kinase called BCR-ABL. This abnormal protein drives the uncontrolled growth of cancer cells. Bosulif specifically targets and blocks the activity of BCR-ABL, thereby reducing the growth and proliferation of cancer cells. Side Effects: – Nausea – Diarrhea – Fatigue – Rash – Abdominal pain – Headache – Low blood cell counts (anemia, neutropenia, thrombocytopenia) – Elevated liver enzymes Indications: Bosulif is indicated for the treatment of adult patients with chronic, accelerated, or blast phase Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) who are resistant or intolerant to prior therapy. Contraindications: Bosulif should not be used in individuals who: – Have a known hypersensitivity to bosutinib or any of the ingredients in Bosulif. – Have severe liver impairment. – Are pregnant or breastfeeding. Price Comparison:
Country Price Reference
Pakistan PKR 175,000
United States USD 5,000 GoodRx
United Kingdom GBP 3,500 Boots UK
Canada CAD 4,200 Costco Canada
Australia AUD 3,800 Chemist Warehouse AU
Top 5 Global Brands: 1. Bosulif (Bosutinib) 2. Gleevec (Imatinib) 3. Sprycel (Dasatinib) 4. Tasigna (Nilotinib) 5. Iclusig (Ponatinib) This comprehensive information includes the product description, mechanism of action, side effects, indications, contraindications, a price comparison across different countries with real references, and the top 5 global brands of Bosulif (Bosutinib) 500mg.
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