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  • Cibinqo (abrocitinib) 200mg

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    Description

    Cibinqo (abrocitinib) is a medication primarily used to treat moderate to severe atopic dermatitis (eczema) in patients 12 years and older who have not responded adequately to other systemic treatments. It is an oral Janus kinase (JAK) inhibitor that helps reduce inflammation by blocking specific pathways (JAK-STAT pathways) that contribute to the immune system’s response to eczema.

    How It Works:

    Abrocitinib works by inhibiting the Janus kinase (JAK) enzymes, which play a critical role in the signaling pathways that regulate immune responses. In atopic dermatitis, cytokines such as IL-4, IL-13, and IL-31 are involved in the inflammation process. By blocking these pathways, abrocitinib reduces the overactive immune response, decreasing inflammation, itching, and other symptoms of eczema.

    Side Effects:

    Common Side Effects include:
    • Nausea
    • Headache
    • Acne
    • Upper respiratory tract infections
    • Dizziness
    • Herpes simplex infection
    Serious Side Effects (less common) include:
    • Blood clots (venous thromboembolism)
    • Serious infections (viral, bacterial, fungal)
    • Thrombocytopenia (low platelets)
    • Risk of lymphoma and other cancers

      Indications:

      Cibinqo is indicated for:
      • Moderate to severe atopic dermatitis in patients aged 12 years and older who have not responded to other systemic treatment.

        Contraindications:

        Cibinqo should not be used if:
        • You have a serious systemic infection, including active tuberculosis.
        • You have severe liver disease.
        • You are pregnant or breastfeeding.
        • You have a hypersensitivity to abrocitinib or its ingredients

          Price in Different Countries:

          Country Price Source
          United States ~$5,500 Drugs.com
          United Kingdom ~£2,000 NHS UK
          Australia ~AUD 3,500 TGA Australia
          Canada ~CAD 4,800 CADTH
          Germany ~€4,200 Pharmazeutische Zeitung

          Top 5 Global Brands:

          1. Pfizer (manufacturer of Cibinqo)
          2. Novartis
          3. Roche
          4. Johnson & Johnson
          5. Sanofi
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    Cibinqo (abrocitinib) 200mg
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