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DARZALEX (daratumumab) is a medication primarily used to treat multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. It belongs to a class of drugs known as monoclonal antibodies. Mechanism of Action: DARZALEX works by targeting and binding to a protein called CD38, which is highly expressed on the surface of multiple myeloma cells. By binding to CD38, DARZALEX triggers a series of immune responses that lead to the destruction of myeloma cells, including antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and apoptosis. Benefits: The benefits of DARZALEX include:
  • Treatment of multiple myeloma in various settings, including newly diagnosed patients, relapsed or refractory disease, and as maintenance therapy.
  • Improved response rates, progression-free survival, and overall survival in clinical trials when used alone or in combination with other medications.
  • Reduction in symptoms associated with multiple myeloma, such as bone pain, anemia, and kidney dysfunction.
Dosage and Administration: DARZALEX is administered intravenously (into a vein) as an infusion. The recommended dosage and administration schedule may vary depending on the specific treatment regimen and the patient’s individual characteristics, including weight, medical history, and treatment response. Healthcare professionals typically determine the appropriate dose and infusion schedule. Suitability: DARZALEX is indicated for the treatment of multiple myeloma and is typically prescribed by hematologists or oncologists. The suitability of DARZALEX for an individual patient is determined based on factors such as disease stage, prior treatments received, overall health status, and any underlying medical conditions. Availability: DARZALEX is available by prescription only and is administered in medical facilities equipped to administer intravenous medications, such as hospitals, infusion centers, or outpatient clinics. As for the prices of DARZALEX 100 MG/5 ML INFUZYONLUK COZELTI in different countries, specific pricing information would need to be obtained from pharmaceutical databases, local pharmacies, or healthcare providers in those regions.
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