Estromarin cream 42.5 g

Estromarin Vaginal Cream is a topical hormone replacement therapy containing estrogen, specifically designed for intravaginal use. It is commonly prescribed for women experiencing symptoms of menopause, such as vaginal dryness, itching, and burning. The cream helps replenish estrogen levels locally, which alleviates these symptoms and improves vaginal health.

How It Works

Estromarin Vaginal Cream works by delivering estrogen directly to the vaginal tissues. Estrogen is a hormone that plays a key role in maintaining the health and function of the vaginal and urinary tissues. During menopause, estrogen levels decline, leading to symptoms like vaginal dryness, thinning of the vaginal walls, and decreased elasticity. By applying the cream directly to the vaginal area, estrogen is absorbed into the tissues, helping to restore moisture, thickness, and elasticity. This localized approach minimizes systemic absorption, reducing the risk of side effects compared to oral hormone replacement therapy.

Side Effects

• Vaginal irritation or itching
• Headache
• Nausea
• Breast tenderness
• Breakthrough bleeding
• Increased vaginal discharge
• Abdominal cramps
• Fluid retention
• Weight changes
• Mood changes

Indications

Estromarin Vaginal Cream is primarily indicated for:

• Treatment of moderate to severe vaginal atrophy due to menopause
• Relief of symptoms such as vaginal dryness, itching, and burning
• Prevention of vaginal and urinary tract infections in postmenopausal women

Contraindications

• Known or suspected breast cancer
• Estrogen-dependent neoplasia
• Undiagnosed abnormal genital bleeding
• Active or history of venous thromboembolism (e.g., deep vein thrombosis, pulmonary embolism)
• Active or recent arterial thromboembolic disease (e.g., stroke, myocardial infarction)
• Severe liver dysfunction
• Pregnancy
• Hypersensitivity to any component of the cream

Price Comparison in Different Countries

Country	Price (per tube)	Reference
Pakistan	PKR 3,200	medicalstore.com.pk
United States	USD 40 – 60	GoodRx
United Kingdom	GBP 30 – 50	NHS UK
Canada	CAD 50 – 70	Canada Drugs
Australia	AUD 60 – 80	PBS Australia

Top 5 Global Brands

1. Estrace (Allergan)
2. Premarin (Pfizer)
3. Ovestin (Aspen Pharmacare)
4. Estriol (Watson Pharma)
5. Vagifem (Novo Nordisk)