EVENITY 105 mg solution for injection in pre-filled pen


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How It Works

Evenity (romosozumab) is a monoclonal antibody that works by inhibiting sclerostin, a protein that regulates bone metabolism. By blocking sclerostin, Evenity increases bone formation and decreases bone resorption, leading to a net gain in bone density and strength. This dual effect on bone turnover helps to reduce the risk of fractures in individuals with osteoporosis.

List of Side Effects

  • Joint pain
  • Headache
  • Injection site reactions
  • Muscle spasms
  • Swelling of the hands, ankles, or feet
  • Fatigue
  • Allergic reactions
  • Increased risk of heart attack or stroke
  • Hypocalcemia (low calcium levels)

List of Indications

  • Treatment of osteoporosis in postmenopausal women at high risk for fracture, defined as a history of osteoporotic fracture or multiple risk factors for fracture
  • Treatment of osteoporosis in men at high risk for fracture

List of Contraindications

  • Hypocalcemia
  • Known hypersensitivity to romosozumab or any of its excipients
  • History of myocardial infarction or stroke
  • Patients with a high risk of cardiovascular disease

Price in Different Countries

Country Price (USD) Reference Website
United States $1,825 GoodRx
United Kingdom ?1,400 NICE BNF
Canada $2,300 CAD CanadaDrugs.com
Australia $2,600 AUD PBS Australia
India ?150,000 INR 1mg
Pakistan ? 320,000 PKR Dawaai.pk

Top 5 Global Brands

  1. Evenity (Romosozumab) – Amgen and UCB
  2. Prolia (Denosumab) – Amgen
  3. Forteo (Teriparatide) – Eli Lilly
  4. Reclast (Zoledronic acid) – Novartis
  5. Boniva (Ibandronate) – Roche
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