GEMTESA 75 mg (vibegron ) 90 Tablets

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Description

GEMTESA, containing the active ingredient vibegron, is a prescription medication used to treat overactive bladder (OAB) in adults. It helps to relax the bladder muscles and reduce symptoms such as frequent urination, urgent need to urinate, and urinary incontinence. GEMTESA is available in tablet form with a dosage strength of 75 mg, and it is typically prescribed as a 90-tablet supply.

How It Works

Vibegron, the active ingredient in GEMTESA, is a beta-3 adrenergic agonist. It works by stimulating beta-3 adrenergic receptors in the bladder. Activation of these receptors relaxes the detrusor muscle during the storage phase of the bladder fill-void cycle, which increases bladder capacity and reduces the symptoms of overactive bladder. This helps to decrease the frequency and urgency of urination, as well as reduce episodes of urinary incontinence.

Side Effects

  • Headache
  • Nausea
  • Diarrhea
  • Upper respiratory tract infection
  • Urinary tract infection
  • Dizziness
  • Back pain
  • Abdominal pain

Indications

  • Treatment of overactive bladder (OAB) in adults with symptoms of urinary frequency, urgency, and urge urinary incontinence.

Contraindications

  • Severe hypersensitivity (e.g., anaphylaxis, angioedema) to vibegron or any component of the formulation.
  • Patients with severe hepatic impairment.
  • Patients with severe renal impairment or end-stage renal disease.

Price in Different Countries

Country Price (USD) Reference
United States $450 GoodRx
United Kingdom ?350 NHS UK
Canada CAD 600 Canada Drugs
Australia AUD 650 PBS Australia
Germany ?400 Gelbe Liste

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