Ilaris (canakinumab) for injection 180mg sterile powder

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Description

How It Works

Ilaris (canakinumab) is a monoclonal antibody that targets interleukin-1 beta (IL-1?), a pro-inflammatory cytokine involved in various inflammatory diseases. By binding to IL-1?, canakinumab prevents it from interacting with its receptors, thereby inhibiting the inflammatory response. This mechanism is particularly beneficial in conditions where IL-1? plays a key role in driving inflammation, helping to reduce symptoms and prevent flare-ups.

List of Side Effects

  • Infections (e.g., upper respiratory tract infections)
  • Injection site reactions
  • Abdominal pain
  • Headache
  • Diarrhea
  • Cold symptoms (nasopharyngitis)
  • Flu-like symptoms
  • Dizziness
  • Nausea
  • Back pain

List of Indications

  • Periodic fever syndromes including:
    • Cryopyrin-Associated Periodic Syndromes (CAPS) in adults and children aged 4 years and older, including Familial Cold Autoinflammatory Syndrome (FCAS) and Muckle-Wells Syndrome (MWS)
    • Systemic Juvenile Idiopathic Arthritis (SJIA) in patients aged 2 years and older
    • Adult-Onset Still’s Disease (AOSD)
  • Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)
  • Hyperimmunoglobulin D Syndrome (HIDS)/Mevalonate Kinase Deficiency (MKD)
  • Familial Mediterranean Fever (FMF)

List of Contraindications

  • Known hypersensitivity to canakinumab or any of its excipients
  • Active severe infections

Price in Different Countries

Country Price (USD) Reference Website
United States $16,000 GoodRx
United Kingdom ?12,000 NICE BNF
Canada $21,000 CAD CanadaDrugs.com
Australia $24,000 AUD PBS Australia
India ?1,200,000 INR 1mg
Pakistan ? 2,500,000 PKR Dawaai.pk

Top 5 Global Brands

  1. Ilaris (Canakinumab) – Novartis
  2. Kineret (Anakinra) – Swedish Orphan Biovitrum
  3. Actemra (Tocilizumab) – Roche
  4. Humira (Adalimumab) – AbbVie
  5. Enbrel (Etanercept) – Amgen
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