Ilaris (canakinumab) for injection 180mg sterile powder
Condition : New
0
From UAE
To United States
in 5-10 days
Description
How It Works
Ilaris (canakinumab) is a monoclonal antibody that targets interleukin-1 beta (IL-1?), a pro-inflammatory cytokine involved in various inflammatory diseases. By binding to IL-1?, canakinumab prevents it from interacting with its receptors, thereby inhibiting the inflammatory response. This mechanism is particularly beneficial in conditions where IL-1? plays a key role in driving inflammation, helping to reduce symptoms and prevent flare-ups.List of Side Effects
- Infections (e.g., upper respiratory tract infections)
- Injection site reactions
- Abdominal pain
- Headache
- Diarrhea
- Cold symptoms (nasopharyngitis)
- Flu-like symptoms
- Dizziness
- Nausea
- Back pain
List of Indications
- Periodic fever syndromes including:
- Cryopyrin-Associated Periodic Syndromes (CAPS) in adults and children aged 4 years and older, including Familial Cold Autoinflammatory Syndrome (FCAS) and Muckle-Wells Syndrome (MWS)
- Systemic Juvenile Idiopathic Arthritis (SJIA) in patients aged 2 years and older
- Adult-Onset Still’s Disease (AOSD)
- Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)
- Hyperimmunoglobulin D Syndrome (HIDS)/Mevalonate Kinase Deficiency (MKD)
- Familial Mediterranean Fever (FMF)
List of Contraindications
- Known hypersensitivity to canakinumab or any of its excipients
- Active severe infections
Price in Different Countries
Country | Price (USD) | Reference Website |
---|---|---|
United States | $16,000 | GoodRx |
United Kingdom | ?12,000 | NICE BNF |
Canada | $21,000 CAD | CanadaDrugs.com |
Australia | $24,000 AUD | PBS Australia |
India | ?1,200,000 INR | 1mg |
Pakistan | ? 2,500,000 PKR | Dawaai.pk |
Top 5 Global Brands
- Ilaris (Canakinumab) – Novartis
- Kineret (Anakinra) – Swedish Orphan Biovitrum
- Actemra (Tocilizumab) – Roche
- Humira (Adalimumab) – AbbVie
- Enbrel (Etanercept) – Amgen