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  • Ilaris (canakinumab) for injection 180mg sterile powder

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    Description

    How It Works

    Ilaris (canakinumab) is a monoclonal antibody that targets interleukin-1 beta (IL-1?), a pro-inflammatory cytokine involved in various inflammatory diseases. By binding to IL-1?, canakinumab prevents it from interacting with its receptors, thereby inhibiting the inflammatory response. This mechanism is particularly beneficial in conditions where IL-1? plays a key role in driving inflammation, helping to reduce symptoms and prevent flare-ups.

    List of Side Effects

    • Infections (e.g., upper respiratory tract infections)
    • Injection site reactions
    • Abdominal pain
    • Headache
    • Diarrhea
    • Cold symptoms (nasopharyngitis)
    • Flu-like symptoms
    • Dizziness
    • Nausea
    • Back pain

    List of Indications

    • Periodic fever syndromes including:
      • Cryopyrin-Associated Periodic Syndromes (CAPS) in adults and children aged 4 years and older, including Familial Cold Autoinflammatory Syndrome (FCAS) and Muckle-Wells Syndrome (MWS)
      • Systemic Juvenile Idiopathic Arthritis (SJIA) in patients aged 2 years and older
      • Adult-Onset Still’s Disease (AOSD)
    • Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)
    • Hyperimmunoglobulin D Syndrome (HIDS)/Mevalonate Kinase Deficiency (MKD)
    • Familial Mediterranean Fever (FMF)

    List of Contraindications

    • Known hypersensitivity to canakinumab or any of its excipients
    • Active severe infections

    Price in Different Countries

    Country Price (USD) Reference Website
    United States $16,000 GoodRx
    United Kingdom ?12,000 NICE BNF
    Canada $21,000 CAD CanadaDrugs.com
    Australia $24,000 AUD PBS Australia
    India ?1,200,000 INR 1mg
    Pakistan ? 2,500,000 PKR Dawaai.pk

    Top 5 Global Brands

    1. Ilaris (Canakinumab) – Novartis
    2. Kineret (Anakinra) – Swedish Orphan Biovitrum
    3. Actemra (Tocilizumab) – Roche
    4. Humira (Adalimumab) – AbbVie
    5. Enbrel (Etanercept) – Amgen
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    Ilaris (canakinumab) for injection 180mg sterile powder
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