Insulin Glargine Injection (RDNA Origin) (Basalog One)

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Description

How it Works

Insulin glargine, marketed under the brand name Basalog One, is a long-acting recombinant DNA-origin human insulin analog used to improve blood sugar control in people with diabetes mellitus. It works by providing a steady level of insulin in the body, mimicking the natural basal insulin secretion. Insulin glargine has a prolonged duration of action, lasting up to 24 hours, which helps maintain stable blood glucose levels throughout the day and night, reducing the risk of hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).

Side Effects

  • Hypoglycemia (low blood sugar)
  • Injection site reactions (e.g., pain, redness, swelling)
  • Weight gain
  • Edema (swelling)
  • Lipodystrophy (changes in fat tissue at the injection site)
  • Allergic reactions (e.g., rash, itching, shortness of breath)
  • Visual disturbances
  • Hypokalemia (low potassium levels)

Indications

  • Type 1 diabetes mellitus in adults and pediatric patients
  • Type 2 diabetes mellitus in adults who require long-acting basal insulin for glycemic control

Contraindications

  • Hypersensitivity to insulin glargine or any of its components
  • During episodes of hypoglycemia

Price Comparison in Different Countries

Country Price (USD) Website
United States $300 GoodRx
Canada $100 PharmacyChecker
United Kingdom ?70 NHS
Australia AUD 150 PBS
India ?2,000 Medindia

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