Kerendia 10 mg film coated tablets

Kerendia (finerenone) is a medication used to treat chronic kidney disease (CKD) and diabetic kidney disease in adults. It is formulated as 10 mg film-coated tablets and belongs to a class of drugs known as non-steroidal mineralocorticoid receptor antagonists (MRAs). Kerendia helps manage kidney function by targeting the mineralocorticoid receptors, which play a role in regulating fluid balance and blood pressure.

How It Works

Kerendia (finerenone) works by selectively inhibiting mineralocorticoid receptors in the kidney. Unlike traditional MRAs, Kerendia does not have the same steroidal structure, which allows it to target the receptors more specifically. By blocking these receptors, Kerendia reduces inflammation and fibrosis in the kidney, thereby helping to preserve kidney function and reduce the risk of progression to end-stage kidney disease. It also helps in controlling blood pressure and managing fluid balance.

Side Effects

• Hyperkalemia (elevated potassium levels)
• Dehydration
• Low blood pressure
• Fatigue
• Nausea
• Headache
• Kidney function abnormalities
• Dizziness
• Muscle pain

Indications

• Management of chronic kidney disease (CKD) in patients with type 2 diabetes.
• Reduction of risk of kidney function decline and cardiovascular events in diabetic kidney disease.

Contraindications

• Known hypersensitivity to finerenone or any of the components of Kerendia.
• Severe renal impairment or end-stage renal disease requiring dialysis.
• Severe hyperkalemia (elevated potassium levels) that cannot be managed by other means.
• Pregnancy and breastfeeding (unless specifically advised by a healthcare provider).

Price in Different Countries

Country	Price (per 10 mg tablet)	References
United States	$9 per tablet	GoodRx Kerendia Price
United Kingdom	£7 per tablet	NHS Kerendia Price
Canada	$8 per tablet	Canada Drugs Kerendia Price
Australia	$10 per tablet	PBS Kerendia Price
India	₹600 per tablet	1mg Kerendia Price

Top 5 Global Brands

• Kerendia (Bayer): The primary brand for finerenone, specifically used for managing CKD and diabetic kidney disease.
• Farxiga (AstraZeneca): Another drug used for chronic kidney disease and diabetes management, with different mechanisms.
• Jardiance (Boehringer Ingelheim): Used for type 2 diabetes and CKD with a different mechanism of action.
• Invokana (Janssen): Used for type 2 diabetes and CKD, with a different approach to managing blood glucose levels.
• Entresto (Novartis): A medication for heart failure that can also impact kidney function, but works differently from Kerendia.