Kesimpta 20 mg solution for injection in pre-filled pen

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Description

How It Works

Kesimpta (generic name ofatumumab) is a human monoclonal antibody that targets a protein called CD20, which is found on the surface of B-lymphocytes. By binding to CD20, Kesimpta selectively depletes B-lymphocytes from the bloodstream. B-lymphocytes play a role in the immune response, including the production of antibodies. In certain autoimmune diseases like multiple sclerosis, B-lymphocytes are thought to contribute to the inflammatory process that damages nerve cells. By depleting B-lymphocytes, Kesimpta helps to reduce inflammation and slow down the progression of multiple sclerosis.

Side Effects

  • Injection site reactions
  • Upper respiratory tract infections
  • Headache
  • Fatigue
  • Herpes viral infections

Indications

  • Kesimpta is indicated for the treatment of relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome (CIS), relapsing-remitting disease, and active secondary progressive disease, in adults.

Contraindications

  • Hypersensitivity to ofatumumab or any component of the formulation
  • Active systemic infections
  • Patients with active hepatitis B infection

Price Comparison in Different Countries

Country Price (per pre-filled pen) Website
United States $5,000 GoodRx
United Kingdom ?4,000 NHS
Australia AUD 6,000 PBS Australia
Canada CAD 7,000 CADTH
Germany ?5,000 Apotheken Umschau

Top 5 Global Brands

  1. Pfizer
  2. Roche
  3. Novartis
  4. Merck & Co.
  5. Johnson & Johnson
 
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