KEYTRUDA 100 MG/ 4 ML IV FLC
Condition : New
0
From UAE
To United States
in 5-10 days
Description
KEYTRUDA is a prescription medication used in immunotherapy to treat various types of cancer. It contains the active ingredient pembrolizumab, which is a monoclonal antibody designed to inhibit the programmed cell death protein 1 (PD-1) receptor. By blocking PD-1, KEYTRUDA helps to enhance the body’s immune system to recognize and attack cancer cells.
How It Works
KEYTRUDA is an immune checkpoint inhibitor. It works by targeting and blocking the PD-1 receptor on the surface of immune cells. Normally, the PD-1 receptor helps prevent immune cells from attacking normal cells. Cancer cells often exploit this pathway to evade immune detection and destruction. By inhibiting PD-1, KEYTRUDA helps the immune system to recognize and destroy cancer cells more effectively.
Indications
KEYTRUDA is approved for the treatment of several types of cancer, including:
Non-Small Cell Lung Cancer (NSCLC)
Melanoma
Head and Neck Squamous Cell Carcinoma (HNSCC)
Hodgkin Lymphoma
Urothelial Carcinoma
Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Solid Tumors
Esophageal Cancer
Primary Mediastinal B-Cell Lymphoma (PMBCL)
Cervical Cancer
Cutaneous Squamous Cell Carcinoma (CSCC)
Side Effects
Common side effects of KEYTRUDA include:
Fatigue
Nausea
Pruritus (itching)
Rash
Decreased appetite
Diarrhea
Cough
Fever
Serious side effects may include:
Immune-mediated pneumonitis (lung inflammation)
Immune-mediated colitis (inflammation of the colon)
Immune-mediated hepatitis (liver inflammation)
Immune-mediated endocrinopathies (endocrine gland inflammation)
Severe infections
Infusion reactions
Contraindications
KEYTRUDA is contraindicated in:
Patients with a known hypersensitivity to pembrolizumab or any of the excipients of the product.
Patients with severe, active autoimmune diseases that may be exacerbated by immune system activation.
Patients who are pregnant or breastfeeding, due to potential risks to the fetus or infant.
Price Table (in Different Countries)
Below is an HTML table showing approximate prices for KEYTRUDA 100 MG/4 ML IV FLC in various countries. Prices may vary and are subject to change.
Top 5 Global Brands
Merck & Co., Inc. (Manufacturer of KEYTRUDA)
Bristol-Myers Squibb (Known for Opdivo, another PD-1 inhibitor)
Roche (Manufacturer of Tecentriq, an anti-PD-L1 therapy)
AstraZeneca (Known for Imfinzi, another immune checkpoint inhibitor)
Novartis (Manufacturer of Kymriah, though it’s a CAR T-cell therapy, it competes in the immunotherapy space)
KEYTRUDA 100 MG/4 ML IV FLC Price Comparison
Country | Price (USD) | Reference |
---|---|---|
United States | $10,000 | GoodRx |
United Kingdom | £7,500 | NICE |
Canada | CAD $12,000 | CADTH |
Australia | AUD $14,000 | PBS |
Germany | €9,000 | G-BA |