Nplate (Romiplostim) Injection


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How It Works

Nplate (Romiplostim) is a thrombopoietin receptor agonist used to treat thrombocytopenia (low platelet count) in certain conditions. Romiplostim mimics the action of thrombopoietin, a natural protein in the body that regulates platelet production. It binds to and activates the thrombopoietin receptor on megakaryocytes (the bone marrow cells that produce platelets), leading to increased production of platelets. This helps to increase the platelet count in patients, reducing the risk of bleeding.

List of Side Effects

  • Headache
  • Fatigue
  • Joint pain
  • Insomnia
  • Dizziness
  • Nausea
  • Diarrhea
  • Muscle pain
  • Abdominal pain
  • Bone pain
  • Injection site reactions

List of Indications

  • Chronic immune thrombocytopenia (ITP) in adults and children who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy.

List of Contraindications

  • Hypersensitivity to romiplostim or any of its excipients
  • Patients with myelodysplastic syndromes (MDS) due to the potential for increased blast cell formation
  • Patients with active or history of thromboembolism

Price in Different Countries

Country Price (USD) Reference Website
United States $2,200 GoodRx
United Kingdom ?1,800 NICE BNF
Canada $2,800 CAD
Australia $3,000 AUD PBS Australia
India ?160,000 INR 1mg
Pakistan ? 300,000 PKR

Top 5 Global Brands

  1. Nplate (Romiplostim) – Amgen
  2. Promacta (Eltrombopag) – Novartis
  3. Revolade (Eltrombopag) – Novartis
  4. Doptelet (Avatrombopag) – Dova Pharmaceuticals
  5. Mulpleta (Lusutrombopag) – Shionogi
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