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  • Nplate (Romiplostim) Injection

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    Description

    How It Works

    Nplate (Romiplostim) is a thrombopoietin receptor agonist used to treat thrombocytopenia (low platelet count) in certain conditions. Romiplostim mimics the action of thrombopoietin, a natural protein in the body that regulates platelet production. It binds to and activates the thrombopoietin receptor on megakaryocytes (the bone marrow cells that produce platelets), leading to increased production of platelets. This helps to increase the platelet count in patients, reducing the risk of bleeding.

    List of Side Effects

    • Headache
    • Fatigue
    • Joint pain
    • Insomnia
    • Dizziness
    • Nausea
    • Diarrhea
    • Muscle pain
    • Abdominal pain
    • Bone pain
    • Injection site reactions

    List of Indications

    • Chronic immune thrombocytopenia (ITP) in adults and children who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy.

    List of Contraindications

    • Hypersensitivity to romiplostim or any of its excipients
    • Patients with myelodysplastic syndromes (MDS) due to the potential for increased blast cell formation
    • Patients with active or history of thromboembolism

    Price in Different Countries

    Country Price (USD) Reference Website
    United States $2,200 GoodRx
    United Kingdom ?1,800 NICE BNF
    Canada $2,800 CAD CanadaDrugs.com
    Australia $3,000 AUD PBS Australia
    India ?160,000 INR 1mg
    Pakistan ? 300,000 PKR Dawaai.pk

    Top 5 Global Brands

    1. Nplate (Romiplostim) – Amgen
    2. Promacta (Eltrombopag) – Novartis
    3. Revolade (Eltrombopag) – Novartis
    4. Doptelet (Avatrombopag) – Dova Pharmaceuticals
    5. Mulpleta (Lusutrombopag) – Shionogi
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    Nplate (Romiplostim) Injection
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