Nuplazid 17mg (Pimavanserin ) 60 tabets

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Description

Nuplazid (pimavanserin) is an atypical antipsychotic medication specifically approved for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis. Each tablet contains 17mg of pimavanserin, and a standard prescription includes 60 tablets.

How It Works

Pimavanserin works by selectively targeting and modulating serotonin receptors, specifically the 5-HT2A receptors. Unlike other antipsychotics, it does not significantly interact with dopamine receptors. This selectivity helps to manage the psychotic symptoms without exacerbating the motor symptoms of Parkinson’s disease. By blocking or inhibiting the 5-HT2A receptors, pimavanserin reduces the occurrence of hallucinations and delusions.

Indications

  • Hallucinations and delusions associated with Parkinson’s disease psychosis

Contraindications

  • Known hypersensitivity to pimavanserin or any of the excipients in the formulation
  • Patients with a history of cardiac arrhythmias or those taking other medications known to prolong the QT interval
  • Severe hepatic impairment
  • Concurrent use of strong CYP3A4 inhibitors or inducers

Side Effects

  • Peripheral edema
  • Nausea
  • Confusional state
  • Hallucinations (worsening)
  • QT interval prolongation
  • Urinary tract infection
  • Fatigue
  • Insomnia
  • Abdominal pain
  • Headache

Price in Different Countries

Country Price (per pack of 60 tablets) References
United States $3,500 GoodRx Nuplazid Price
United Kingdom ?2,700 NHS Nuplazid Price
Canada $4,000 Canada Drugs Nuplazid Price
Australia $3,800 PBS Nuplazid Price
India ?280,000 1mg Nuplazid Price

Top 5 Global Brands

  • Nuplazid (Acadia Pharmaceuticals): The primary and original brand of pimavanserin, widely used for treating Parkinson’s disease psychosis.
  • Seroquel (AstraZeneca): Though primarily used for schizophrenia and bipolar disorder, Seroquel is also prescribed off-label for similar psychotic symptoms.
  • Zyprexa (Eli Lilly): Another antipsychotic that, while not as selective as Nuplazid, is used to treat various psychoses including off-label uses.
  • Risperdal (Janssen Pharmaceuticals): Commonly used for schizophrenia and bipolar disorder, it is also prescribed off-label for psychosis in Parkinson’s disease.
  • Abilify (Otsuka Pharmaceutical): Used for various psychiatric conditions including schizophrenia and bipolar disorder, it is also an option for psychosis treatment.
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