Orgovyx (Relugolix) 120 mg Tablet

Orgovyx, containing the active ingredient relugolix, is a prescription medication available in a 120 mg tablet form. It is used primarily for the treatment of advanced prostate cancer. Relugolix is a non-peptide, oral GnRH (gonadotropin-releasing hormone) receptor antagonist that helps to lower levels of testosterone, which is crucial in the treatment of hormone-sensitive prostate cancer.

How It Works

Relugolix, the active ingredient in Orgovyx, works by directly blocking GnRH receptors in the pituitary gland. This inhibition reduces the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to a significant decrease in testosterone levels in men. Lower testosterone levels can slow down or stop the growth of prostate cancer cells that are dependent on testosterone for their growth.

Side Effects

• Hot flashes
• Fatigue
• Nausea
• Headache
• Diarrhea
• Abdominal pain
• Weight gain
• Reduced libido
• Muscle pain
• Increased risk of cardiovascular events (e.g., heart attack, stroke)

Indications

• Management of advanced prostate cancer in adult men.
• Use as part of a comprehensive treatment plan for hormone-sensitive prostate cancer.

Contraindications

• Hypersensitivity to relugolix or any of its components.
• Severe hepatic impairment (liver disease), as the drug is metabolized by the liver.
• Concurrent use with strong inhibitors or inducers of cytochrome P450 3A4 (e.g., ketoconazole, rifampin) may alter drug levels and effectiveness.
• Patients with a history of severe cardiovascular events may need to be monitored closely due to potential cardiovascular risks associated with the drug.
• Pregnant or breastfeeding women, as the safety of Orgovyx in these populations has not been established.

Price in Different Countries

Country	Price (per 120 mg Tablet)	References
United States	$6,000 per 30 tablets	GoodRx Orgovyx Price
United Kingdom	£4,500 per 30 tablets	NHS Relugolix Price
Canada	$6,500 per 30 tablets	Canadian Pharmacy Orgovyx Price
Australia	$6,200 per 30 tablets	PBS Orgovyx Price
India	₹45,000 per 30 tablets	1mg Orgovyx Price

Top 5 Global Brands

• Orgovyx (Myovant Sciences): The original branded medication containing relugolix for the treatment of advanced prostate cancer.
• Relugolix (Various Generic Manufacturers): Generic versions of relugolix may be available as alternatives to the branded Orgovyx.
• Myovant Sciences: The company that markets Orgovyx and is involved in the development of relugolix-based treatments.
• Relugolix Therapy (Pharmaco): Offers relugolix products for managing prostate cancer.
• ProstateCare (ProstateCare Pharmaceuticals): Provides various options for hormone-sensitive prostate cancer treatment, including relugolix-based therapies.