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  • Piqray (Alpelisib) 300mg film-coated tablets

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    Description

    How It Works

    Piqray works by inhibiting a protein called phosphatidylinositol 3-kinase (PI3K). PI3K is involved in cell growth, survival, and metabolism. By blocking PI3K, Piqray helps slow down or stop the growth of cancer cells in patients with advanced breast cancer that have a specific genetic mutation known as PIK3CA mutation.

    Side Effects

    • Hyperglycemia (high blood sugar)
    • Nausea
    • Fatigue
    • Rash
    • Diarrhea
    • Decreased appetite

    Indications

    • Piqray is indicated in combination with fulvestrant for the treatment of postmenopausal women, and men, with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer as detected by an FDA-approved test following progression on or after an endocrine-based regimen.

    Contra indications

    • Hypersensitivity to alpelisib or any of the excipients
    • Severe hepatic impairment

    Price Comparison in Different Countries

    Country Price (USD) Reference
    United States $12,000.00 GoodRx
    United Kingdom ?9,000.00 NHS UK
    Australia $15,000.00 AUD Pharmaceutical Benefits Scheme Australia
    Canada $13,000.00 CAD MedBroadcast Canada

    Top 5 Global Brands

    1. Novartis
    2. Pfizer
    3. Roche
    4. Merck & Co.
    5. Sanofi
     
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    Piqray (Alpelisib) 300mg film-coated tablets
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