Pomalyst 4mg Capsules

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Description

Pomalyst (pomalidomide) 4mg capsules are used in the treatment of multiple myeloma, a type of cancer that affects plasma cells. Pomalyst is typically used in patients who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor, and have demonstrated disease progression on or within 60 days of completion of the last therapy.

How It Works

Pomalyst contains pomalidomide, which is an immunomodulatory agent. It works by enhancing the immune system’s ability to fight cancer and inhibiting the growth of cancer cells. Pomalidomide has anti-angiogenic properties, meaning it can prevent the formation of new blood vessels that tumors need to grow. It also promotes apoptosis (programmed cell death) of cancer cells.

Side Effects

  • Neutropenia
  • Fatigue
  • Anemia
  • Thrombocytopenia
  • Constipation
  • Nausea
  • Fever
  • Diarrhea
  • Weakness
  • Upper respiratory tract infection
  • Back pain

Indications

  • Multiple myeloma in patients who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on or within 60 days of completion of the last therapy.

Contraindications

  • Pregnancy (due to the risk of severe birth defects or death to an unborn baby)
  • Hypersensitivity to pomalidomide or any of the excipients in the formulation

Price Comparison in Different Countries

Country Price (per bottle of 21 capsules) Reference
Pakistan Approximately PKR 600,000 Dawaai Pakistan
United States USD 16,000 GoodRx
United Kingdom GBP 12,000 NHS UK
Canada CAD 20,000 MedBroadcast Canada
Australia AUD 22,000 PBS Australia

Top 5 Global Brands

  1. Celgene (a subsidiary of Bristol-Myers Squibb)
  2. Novartis
  3. Pfizer
  4. Roche
  5. Johnson & Johnson

Conclusion

Pomalyst (pomalidomide) 4mg capsules are an important treatment option for patients with multiple myeloma, particularly those who have not responded to other therapies. While effective, the medication comes with significant side effects and contraindications that must be carefully managed by healthcare providers. The cost of Pomalyst varies widely across different countries, reflecting the global disparity in healthcare costs. Patients should consult with their healthcare provider to determine if Pomalyst is the right treatment for their condition and to discuss potential financial assistance options.  
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