Rapatha Injection 140 mg


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How It Works

Rapatha (Evolocumab) 140 mg Injection is a monoclonal antibody used to lower cholesterol levels, particularly low-density lipoprotein cholesterol (LDL-C). It works by inhibiting the proprotein convertase subtilisin/kexin type 9 (PCSK9) enzyme. PCSK9 binds to LDL receptors on the surface of liver cells and leads to their degradation. By blocking PCSK9, evolocumab increases the number of LDL receptors available to clear LDL from the blood, thereby significantly lowering blood cholesterol levels.

List of Side Effects

  • Nasopharyngitis
  • Upper respiratory tract infections
  • Influenza
  • Back pain
  • Injection site reactions (redness, pain, bruising)

List of Indications

  • Primary hyperlipidemia (including heterozygous familial hypercholesterolemia)
  • Homozygous familial hypercholesterolemia
  • Cardiovascular risk reduction in patients with established cardiovascular disease

List of Contraindications

  • Hypersensitivity to evolocumab or any of its excipients
  • Active liver disease
  • Pregnancy
  • Breastfeeding

Price in Different Countries

Country Price (USD) Reference Website
United States $6,000 Drugs.com
United Kingdom ?4,500 NHS UK
Canada $7,500 CAD CanadaDrugs.com
Australia $8,000 AUD Chemist Warehouse
India ?500,000 INR Medlife

Top 5 Global Brands

  1. Rapatha (Evolocumab) – Amgen
  2. Praluent (Alirocumab) – Sanofi/Regeneron
  3. Repatha SureClick (Evolocumab) – Amgen
  4. Lipitor (Atorvastatin) – Pfizer
  5. Crestor (Rosuvastatin) – AstraZeneca
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