Rapatha Injection 140 mgRapatha Injection 140 mg
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Description
How It Works
Rapatha (Evolocumab) 140 mg Injection is a monoclonal antibody used to lower cholesterol levels, particularly low-density lipoprotein cholesterol (LDL-C). It works by inhibiting the proprotein convertase subtilisin/kexin type 9 (PCSK9) enzyme. PCSK9 binds to LDL receptors on the surface of liver cells and leads to their degradation. By blocking PCSK9, evolocumab increases the number of LDL receptors available to clear LDL from the blood, thereby significantly lowering blood cholesterol levels.List of Side Effects
- Nasopharyngitis
- Upper respiratory tract infections
- Influenza
- Back pain
- Injection site reactions (redness, pain, bruising)
List of Indications
- Primary hyperlipidemia (including heterozygous familial hypercholesterolemia)
- Homozygous familial hypercholesterolemia
- Cardiovascular risk reduction in patients with established cardiovascular disease
List of Contraindications
- Hypersensitivity to evolocumab or any of its excipients
- Active liver disease
- Pregnancy
- Breastfeeding
Price in Different Countries
| Country | Price (USD) | Reference Website |
|---|---|---|
| United States | $6,000 | Drugs.com |
| United Kingdom | ?4,500 | NHS UK |
| Canada | $7,500 CAD | CanadaDrugs.com |
| Australia | $8,000 AUD | Chemist Warehouse |
| India | ?500,000 INR | Medlife |
Top 5 Global Brands
- Rapatha (Evolocumab) – Amgen
- Praluent (Alirocumab) – Sanofi/Regeneron
- Repatha SureClick (Evolocumab) – Amgen
- Lipitor (Atorvastatin) – Pfizer
- Crestor (Rosuvastatin) – AstraZeneca