Renflexis (infliximab-abda) for injection 100mg/vial

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Description

Renflexis (infliximab-abda) is a biosimilar to Remicade, used for the treatment of various inflammatory autoimmune diseases. Each vial contains 100 mg of infliximab-abda, a monoclonal antibody that targets tumor necrosis factor-alpha (TNF-alpha), a cytokine involved in systemic inflammation. By inhibiting TNF-alpha, Renflexis helps to reduce inflammation and manage symptoms of autoimmune diseases.

How It Works

Infliximab-abda is a chimeric monoclonal antibody that binds specifically to TNF-alpha, blocking its interaction with TNF receptors on cell surfaces. TNF-alpha is a key cytokine in the inflammatory process, and its inhibition reduces inflammation and modulates the immune response. This action helps to alleviate symptoms and prevent disease progression in conditions such as rheumatoid arthritis, Crohn’s disease, and ulcerative colitis.

Indications

  • Rheumatoid arthritis
  • Crohn’s disease
  • Ulcerative colitis
  • Ankylosing spondylitis
  • Psoriatic arthritis
  • Plaque psoriasis

Contraindications

  • Hypersensitivity to infliximab or any of its components
  • Moderate to severe heart failure
  • Active infections, including tuberculosis

Side Effects

  • Infusion-related reactions (fever, chills, pruritus)
  • Upper respiratory tract infections
  • Headache
  • Abdominal pain
  • Increased liver enzymes
  • Rash
  • Fatigue
  • Urinary tract infections
  • Nausea
  • Back pain

Price in Different Countries

Country Price (per 100mg/vial) References
United States $750 GoodRx Renflexis Price
United Kingdom £600 NHS Renflexis Price
Canada $1,000 Canada Drugs Renflexis Price
Australia $950 PBS Renflexis Price
India ₹50,000 1mg Renflexis Price

Top 5 Global Brands

  • Renflexis (Samsung Bioepis/Merck): The biosimilar to Remicade, used for the treatment of various inflammatory autoimmune diseases.
  • Remicade (Janssen Biotech, Inc.): The original brand of infliximab, widely used for treating autoimmune conditions.
  • Inflectra (Pfizer): Another biosimilar to Remicade, providing similar therapeutic benefits.
  • Remsima (Celltrion Healthcare): A biosimilar infliximab used for treating autoimmune diseases, available in various markets.
  • Flixabi (Biogen): Another infliximab biosimilar, used in the management of inflammatory autoimmune diseases.
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