Rexulti Brexpiprazole 1mg Tablet


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How It Works

Brexpiprazole works by modulating the activity of various neurotransmitters in the brain, primarily serotonin and dopamine. It acts as a partial agonist at serotonin 5-HT1A and dopamine D2 receptors and as an antagonist at serotonin 5-HT2A receptors. By balancing the effects of these neurotransmitters, Brexpiprazole helps improve mood, cognition, and behavior, thereby alleviating symptoms of schizophrenia and depression.

Side Effects

  • Weight gain
  • Restlessness
  • Fatigue
  • Dizziness
  • Increased appetite
  • Upper respiratory tract infection
  • Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  • Headache
  • Diarrhea
  • Anxiety


  • Treatment of schizophrenia
  • Adjunctive treatment of major depressive disorder (MDD)


  • Hypersensitivity to Brexpiprazole or any component of the formulation
  • Severe liver or kidney impairment
  • Use with caution in patients with a history of seizures

Price Comparison in Different Countries

Country Price (per tablet) Reference
Pakistan Approximately PKR 500 Dawaai Pakistan
United States USD 15 GoodRx
United Kingdom GBP 12 NHS UK
Canada CAD 20 Health Canada
Australia AUD 25 PBS Australia

Top 5 Global Brands

  1. Roche
  2. Novartis
  3. Pfizer
  4. Merck & Co.
  5. Johnson & Johnson


Rexulti (Brexpiprazole) 1mg is a crucial medication in the management of schizophrenia and major depressive disorder (MDD). By modulating the activity of serotonin and dopamine in the brain, it helps improve mood and behavior, providing relief to patients suffering from these mental health conditions. While it is generally well-tolerated, it is important to be aware of potential side effects and contraindications. The cost of Rexulti can vary widely across different countries, reflecting disparities in healthcare pricing and accessibility. Patients should consult with their healthcare providers to determine the appropriateness of Rexulti for their needs and to explore any available financial assistance programs.  
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