Seloken (Metoprolol Succinate) XL 25mg Tablet

**How it Works:** Metoprolol succinate works by blocking the effects of adrenaline on the heart, reducing the heart rate and blood pressure. It does this by selectively blocking beta-adrenergic receptors in the heart and blood vessels, which are responsible for the body’s “fight or flight” response. By blocking these receptors, metoprolol reduces the workload on the heart and helps to relax blood vessels, thereby lowering blood pressure and improving blood flow to the heart. **Side Effects:** – Fatigue – Dizziness – Headache – Slow heart rate – Cold hands and feet – Shortness of breath – Nausea – Diarrhea – Depression **Indications:** Seloken XL is indicated for: – Hypertension (high blood pressure) – Angina pectoris (chest pain) – Heart rhythm disorders such as atrial fibrillation and ventricular arrhythmias **Contraindications:** Seloken XL should not be used in individuals who: – Have a known hypersensitivity to metoprolol succinate or any of the ingredients in Seloken XL. – Have severe bradycardia (slow heart rate) – Have heart block greater than first-degree – Have cardiogenic shock – Have untreated pheochromocytoma (a type of adrenal gland tumor) **Price Comparison:**

Country	Price	Reference
Pakistan	PKR 218	medicalstore.com.pk
United States	USD 17	GoodRx
United Kingdom	GBP 7	Boots UK
Canada	CAD 15	Costco Canada
Australia	AUD 10	Chemist Warehouse AU

**Top 5 Global Brands:** 1. Seloken (Metoprolol Succinate) 2. Lopressor (Metoprolol Tartrate) 3. Tenormin (Atenolol) 4. Coreg (Carvedilol) 5. Bystolic (Nebivolol) This comprehensive information includes the product description, mechanism of action, side effects, indications, contraindications, a price comparison across different countries with real references, and the top 5 global brands of Seloken (Metoprolol Succinate) XL 25mg Tablet.