Sivextro Tedizolid Injection, Strength: 200 mg

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Description

Sivextro, with the active ingredient tedizolid phosphate, is an antibiotic used for treating certain bacterial infections. It comes in injection form with a strength of 200 mg. Sivextro is mainly prescribed to manage acute bacterial skin and skin structure infections (ABSSSIs) caused by susceptible bacterial strains.

How It Works

Sivextro, containing tedizolid phosphate, belongs to the oxazolidinone class of antibiotics. It operates by inhibiting bacterial protein synthesis. Tedizolid phosphate binds to the 23S ribosomal RNA of the bacterial 50S ribosomal subunit, which halts the formation of the initiation complex. Consequently, this prevents the assembly of the bacterial ribosome, leading to bacterial cell death.

Side Effects

  • Nausea
  • Headache
  • Vomiting
  • Dizziness
  • Diarrhea
  • Abdominal pain
  • Fatigue
  • Injection site reactions (pain, redness, swelling)
  • Increased liver enzymes

Indications

  • Treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by susceptible strains of bacteria.

Contraindications

  • Known hypersensitivity to tedizolid phosphate or any components of the formulation.
  • Concomitant use of monoamine oxidase inhibitors (MAOIs) or within 2 weeks of stopping an MAOI.

Price in Different Countries

Country Price (USD) Reference
United States $500 GoodRx
United Kingdom ?400 NHS UK
Canada CAD 700 Canada Drugs
Australia AUD 750 PBS Australia
Germany ?480 Gelbe Liste

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