Skyrizi (risankizumab) 150mg injection


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Skyrizi (risankizumab) 150mg is a medication used in the treatment of moderate to severe plaque psoriasis. It is administered via subcutaneous injection and works by targeting specific proteins in the body that contribute to inflammatory conditions.

How It Works

Skyrizi contains risankizumab, a monoclonal antibody that selectively binds to the p19 subunit of interleukin-23 (IL-23). IL-23 is a cytokine that plays a crucial role in the inflammatory process of psoriasis. By inhibiting IL-23, Skyrizi helps to reduce inflammation and the rapid turnover of skin cells, leading to the improvement of psoriatic plaques.

Side Effects

  • Upper respiratory infections
  • Headache
  • Fatigue
  • Injection site reactions
  • Fungal skin infections
  • Itching
  • Back pain


  • Moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.


  • Serious hypersensitivity reactions to risankizumab or any of the excipients in Skyrizi.
  • Active infections, particularly tuberculosis.

Price Comparison in Different Countries

Country Price (per dose) Reference
Pakistan Approximately PKR 300,000 Dawaai Pakistan
United States USD 16,000 GoodRx
United Kingdom GBP 12,000 NHS UK
Canada CAD 20,000 MedBroadcast Canada
Australia AUD 22,000 PBS Australia

Top 5 Global Brands

  1. AbbVie
  2. Novartis
  3. Johnson & Johnson
  4. Pfizer
  5. Roche


Skyrizi (risankizumab) 150mg is a highly effective treatment for moderate to severe plaque psoriasis, offering significant improvements in skin clearance and quality of life for patients. It works by targeting IL-23, a key player in the inflammatory process of psoriasis, and has a favorable safety profile. While it is a costly medication, its effectiveness and the relief it provides make it a valuable option for those struggling with severe psoriasis. Consult with a healthcare provider to determine if Skyrizi is the right treatment for your condition.  
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