Somavert (Pegvisomanto)10mg Injection

Somavert, containing the active ingredient pegvisomant, is a medication provided in a 10 mg injection form. It is primarily used to treat acromegaly, a condition caused by excess growth hormone leading to abnormal growth of tissues and organs. Somavert is specifically designed for patients who have inadequate responses to other treatments for acromegaly.

How It Works

Pegvisomant, the active ingredient in Somavert, is a growth hormone receptor antagonist. It works by binding to growth hormone receptors on target cells, blocking the action of growth hormone. This inhibition prevents the overstimulation of tissues and organs, thereby reducing symptoms associated with excessive growth hormone levels. By counteracting the effects of growth hormone, Somavert helps control the symptoms and complications of acromegaly.

Side Effects

• Injection site reactions (pain, redness, swelling)
• Nausea
• Headache
• Fatigue
• Dizziness
• Abdominal pain
• Diarrhea
• Elevated liver enzymes
• Edema

Indications

• Treatment of acromegaly in adult patients who have had an inadequate response to surgery or radiation therapy, or are not candidates for these treatments.
• Management of acromegaly when other treatments, such as somatostatin analogs, have proven insufficient.

Contraindications

• Hypersensitivity to pegvisomant or any other components of Somavert.
• Patients with severe liver dysfunction or active liver disease.
• Severe allergy reactions or anaphylaxis following pegvisomant administration.
• Pregnant or breastfeeding women unless the potential benefit justifies the risk to the fetus or infant.

Price in Different Countries

Country	Price (per 10 mg Injection)	References
United States	$3,500 per vial	GoodRx Somavert Price
United Kingdom	£2,800 per vial	NHS Pegvisomant Price
Canada	$3,200 per vial	Canadian Pharmacy Somavert Price
Australia	$3,400 per vial	PBS Somavert Price
India	₹2,40,000 per vial	1mg Somavert Price

Top 5 Global Brands

• Somavert (Pfizer): The original brand of pegvisomant, developed and marketed by Pfizer for the treatment of acromegaly.
• Pegvisomant (Various Generic Manufacturers): Generic versions of pegvisomant may be available, providing alternatives to Somavert.
• Endocrine Solutions (Endocrine Solutions): Offers pegvisomant products for specialized hormonal treatments.
• Generic Pegvisomant (Multiple Pharma Companies): Several companies produce generic versions of pegvisomant under different brand names.
• HormoneRx (HormoneRx Pharmaceuticals): Provides pegvisomant products as part of their endocrine treatment options.