Tranexamic Acid Injection (Cyklokapron)

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Description

How it Works

Tranexamic acid, marketed as Cyklokapron, is an antifibrinolytic medication used to prevent or reduce bleeding. It works by inhibiting the activation of plasminogen to plasmin, an enzyme that breaks down fibrin clots. By blocking this activation, tranexamic acid helps stabilize blood clots and prevent excessive bleeding. This mechanism is particularly useful in conditions associated with increased fibrinolysis, where the breakdown of blood clots is accelerated.

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache
  • Allergic skin reactions
  • Thromboembolic events (rare)
  • Visual disturbances
  • Fatigue
  • Muscle pain

Indications

  • Heavy menstrual bleeding
  • Hereditary angioedema
  • Surgery (to reduce perioperative blood loss)
  • Traumatic bleeding
  • Bleeding disorders such as hemophilia
  • Dental procedures in patients with bleeding disorders

Contraindications

  • Hypersensitivity to tranexamic acid or any of its components
  • Active intravascular clotting (e.g., deep vein thrombosis, pulmonary embolism)
  • Subarachnoid hemorrhage
  • Severe renal impairment
  • History of thromboembolic disease

Price Comparison in Different Countries

Country Price (USD) Website
United States $120 GoodRx
Canada $90 PharmacyChecker
United Kingdom ?70 NHS
Australia AUD 150 PBS
India ?4,500 Medindia

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