Trastuzumab For Injection 440mg (Herclon)

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Description

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How It Works

Trastuzumab (marketed as Herclon among other names) is a monoclonal antibody that targets the human epidermal growth factor receptor 2 (HER2). HER2 is a protein that promotes the growth of cancer cells, particularly in breast cancer. Trastuzumab works by binding to HER2 receptors on the surface of cancer cells, which inhibits their growth and signals the immune system to destroy them. This helps to slow or stop the progression of HER2-positive breast cancer.

Side Effects

  • Fatigue
  • Nausea
  • Diarrhea
  • Cardiotoxicity (heart problems)
  • Infusion reactions

Indications

  • Trastuzumab is indicated for the treatment of HER2-positive breast cancer, including:
    • Early-stage breast cancer
    • Metastatic breast cancer
    • Adjuvant treatment after surgery
    • Neoadjuvant treatment before surgery

Contraindications

  • Hypersensitivity to trastuzumab or any component of the formulation
  • Severe congestive heart failure
  • History of severe allergic reactions to other humanized or murine monoclonal antibodies

Price Comparison in Different Countries

Country Price (per injection) Website
United States $2,000 GoodRx
United Kingdom ?1,500 NHS
Australia AUD 3,000 PBS Australia
Canada CAD 3,500 CADTH
Germany ?2,500 Apotheken Umschau

Top 5 Global Brands

  1. Pfizer
  2. Roche
  3. Novartis
  4. Merck & Co.
  5. Johnson & Johnson
 
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