uptravi Selexipag 1000mcg Tablets

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Description

How It Works

Uptravi (Selexipag) is a medication used to treat pulmonary arterial hypertension (PAH). It works by targeting the prostacyclin pathway, which plays a critical role in vascular tone and platelet aggregation. Selexipag is a selective prostacyclin receptor agonist that helps to dilate blood vessels in the lungs, reduce vascular resistance, and improve blood flow. By doing so, it helps to alleviate symptoms, improve exercise capacity, and slow disease progression in patients with PAH.

List of Side Effects

  • Headache
  • Diarrhea
  • Jaw pain
  • Nausea
  • Muscle pain
  • Flushing

List of Indications

  • Pulmonary arterial hypertension (PAH) to delay disease progression and reduce the risk of hospitalization

List of Contraindications

  • Hypersensitivity to selexipag or any of the excipients
  • Severe hepatic impairment
  • Concurrent use with strong CYP2C8 inhibitors (e.g., gemfibrozil)
  • Pregnancy and breastfeeding

Price in Different Countries

Country Price (USD) Reference Website
United States $8,000 Drugs.com
United Kingdom ?6,500 NHS UK
Canada $9,000 CAD CanadaDrugs.com
Australia $10,000 AUD Chemist Warehouse
India ?600,000 INR Medlife

Top 5 Global Brands

  1. Uptravi (Selexipag) – Actelion Pharmaceuticals
  2. Orenitram (Treprostinil) – United Therapeutics
  3. Remodulin (Treprostinil) – United Therapeutics
  4. Adcirca (Tadalafil) – Eli Lilly
  5. Revatio (Sildenafil) – Pfizer
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