Vectibix (Panitumumab) 20mg/ml Injection

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Description

How It Works

Vectibix (panitumumab) is a fully human monoclonal antibody that targets the epidermal growth factor receptor (EGFR). EGFR is a protein found on the surface of both normal and cancer cells, but it is often overexpressed in cancer cells. By binding to EGFR, Vectibix inhibits its activity, preventing the receptor from activating its signaling pathways that promote cell growth and survival. This inhibition helps to slow or stop the growth of cancer cells.

List of Side Effects

  • Skin rash
  • Paronychia (nail infection)
  • Hypomagnesemia (low magnesium levels)
  • Diarrhea
  • Fatigue
  • Nausea
  • Vomiting
  • Stomatitis (inflammation of the mouth and lips)
  • Pruritus (itching)
  • Anemia
  • Hypocalcemia (low calcium levels)

List of Indications

  • Treatment of metastatic colorectal cancer (mCRC) with wild-type RAS (KRAS and NRAS) in patients who have progressed following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing chemotherapy regimens

List of Contraindications

  • Severe hypersensitivity to panitumumab or any of its excipients
  • Interstitial lung disease or pulmonary fibrosis

Price in Different Countries

Country Price (USD) Reference Website
United States $1,200 per vial GoodRx
United Kingdom ?900 per vial NICE BNF
Canada $1,500 CAD per vial CanadaDrugs.com
Australia $1,700 AUD per vial PBS Australia
India ?85,000 INR per vial 1mg
Pakistan ? 300,000 PKR per vial Dawaai.pk

Top 5 Global Brands

  1. Vectibix (Panitumumab) – Amgen
  2. Erbitux (Cetuximab) – Merck KGaA (EMD Serono) and Bristol-Myers Squibb
  3. Cyramza (Ramucirumab) – Eli Lilly and Company
  4. Herceptin (Trastuzumab) – Genentech (Roche)
  5. Avastin (Bevacizumab) – Genentech (Roche)
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