Velsipity (etrasimod) 2mg 30 tablets
Condition : New
0
From UAE
To Pakistan
in 5-10 days
Description
Velsipity (etrasimod) is a once-daily oral medication containing 2 mg of etrasimod, a selective sphingosine 1-phosphate (S1P) receptor modulator used for the treatment of moderate to severe ulcerative colitis. Etrasimod works by modulating immune cell trafficking, thereby helping to manage inflammation in the gastrointestinal tract associated with ulcerative colitis.
How Velsipity Works
Velsipity’s active ingredient, etrasimod, is an S1P receptor modulator that works by selectively targeting the S1P1 receptor. This mechanism helps reduce the migration of lymphocytes (white blood cells) from the lymph nodes to areas of inflammation, particularly in the intestines. By limiting the number of immune cells reaching the gastrointestinal tract, Velsipity helps to reduce inflammation, alleviating symptoms such as abdominal pain, diarrhea, and bleeding in patients with ulcerative colitis. This targeted approach also minimizes systemic immunosuppression, thereby reducing the risk of adverse effects.Indications
Velsipity is primarily indicated for:- Ulcerative Colitis (UC): Approved for the treatment of adults with moderate to severe ulcerative colitis who may not have responded adequately to other treatments.
Side Effects
Common side effects of Velsipity include:- Headache
- Abdominal pain
- Nausea
- Increased liver enzymes
- Respiratory tract infections
- Bradycardia (slow heart rate)
- Increased risk of infections
- Elevated liver enzyme levels
- Macular edema (swelling in the retina)
Contraindications
Velsipity should not be used in the following cases:- Severe Cardiovascular Conditions: Patients with recent heart attack, stroke, or other severe heart conditions.
- Uncontrolled Infections: Patients with active or uncontrolled infections.
- Severe Liver Impairment: Not recommended for patients with severe hepatic impairment.
- Hypersensitivity: Any known allergy to etrasimod or components in the formulation.
Price of Velsipity in Different Countries
The following table provides approximate pricing for Velsipity across different countries. Prices may vary based on pharmacy, insurance coverage, and local pricing regulations.Country | Price (per month supply) | Source |
---|---|---|
United States | $5,000 – $6,500 | GoodRx |
Canada | CAD 6,000 – CAD 7,200 | DrugBank Canada |
United Kingdom | £4,500 – £5,500 | NHS UK |
Australia | AUD 7,000 – AUD 8,500 | PBS Australia |
Germany | €5,000 – €6,000 | Medikamentenpreis Germany |
Top 5 Global Brands for Ulcerative Colitis Treatment
- Velsipity (etrasimod) – A targeted S1P receptor modulator for treating moderate to severe ulcerative colitis.
- Entyvio (vedolizumab) – A monoclonal antibody used for Crohn’s disease and ulcerative colitis, focusing on gut-specific inflammation.
- Humira (adalimumab) – An anti-TNF biologic commonly used in moderate to severe ulcerative colitis.
- Stelara (ustekinumab) – An IL-12 and IL-23 inhibitor effective in treating inflammatory bowel diseases.
- Xeljanz (tofacitinib) – An oral Janus kinase (JAK) inhibitor used for moderate to severe ulcerative colitis.