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VENCLYXTO (venetoclax) 100 mg tablets are typically used in the treatment of chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), often in combination with other medications. Here’s an overview: Pros:
  1. High Efficacy: VENCLYXTO has demonstrated significant efficacy in treating CLL and SLL, particularly in patients with specific genetic mutations like 17p deletion or TP53 mutation.
  2. Oral Administration: The medication comes in tablet form, making it convenient for patients to take at home.
  3. Targeted Therapy: VENCLYXTO selectively inhibits BCL-2, a protein that helps cancer cells survive. This targeted approach can lead to fewer side effects compared to traditional chemotherapy.
  4. Improvement in Overall Survival: Clinical trials have shown that VENCLYXTO, when used in combination with other medications, can prolong overall survival in patients with CLL.
  1. Side Effects: Common side effects of VENCLYXTO include nausea, diarrhea, upper respiratory tract infection, and fatigue. More serious side effects may include tumor lysis syndrome, which requires close monitoring and management.
  2. Cost: VENCLYXTO can be expensive, especially for those without adequate insurance coverage. The price of a 112-tablet pack of VENCLYXTO 100 mg can vary depending on factors such as location and insurance plan.
Price Comparison: The price of VENCLYXTO 100 mg tablets can vary significantly depending on the country, pharmacy, and insurance coverage. In the United States, for example, the average wholesale price (AWP) for a 112-tablet pack of VENCLYXTO 100 mg is around $70,000 to $80,000. However, patients may be eligible for financial assistance programs from the manufacturer or other sources to help cover the cost. Patients should discuss the potential benefits and risks of VENCLYXTO with their healthcare provider, as well as any concerns about affordability. Close monitoring is essential to manage side effects and ensure the best treatment outcomes.
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