Vimpat Lacosamide 100 mg Tablet 60 Tablets

Vimpat (Lacosamide) is a medication primarily used for the treatment of partial-onset seizures in patients with epilepsy. Each tablet contains 100 mg of Lacosamide, a newer antiepileptic drug (AED) that has gained popularity due to its unique mechanism of action and favorable side effect profile. Vimpat is available in various formulations, including oral tablets, oral solution, and injectable forms, making it a versatile choice for epilepsy management.

How It Works

Lacosamide works by selectively enhancing the slow inactivation of voltage-gated sodium channels, which stabilizes hyper-excitable neuronal membranes and inhibits repetitive neuronal firing. This mechanism is distinct from other AEDs, which often target the fast inactivation of sodium channels. By enhancing the slow inactivation, Vimpat can modulate the electrical activity in the brain, reducing the frequency and severity of seizures. This makes it particularly useful for patients who have not responded adequately to other antiepileptic medications.

Side Effects

While Vimpat is generally well-tolerated, some patients may experience side effects. Common side effects include:

• Dizziness
• Headache
• Nausea
• Double vision
• Fatigue
• Sleepiness (somnolence)

In some cases, more serious side effects may occur:

• Cardiac effects, including atrioventricular (AV) block
• Hypersensitivity reactions, including skin rash
• Suicidal thoughts or behavior
• Coordination problems (ataxia)
• Serious allergic reactions, such as swelling of the face, lips, tongue, or throat (angioedema)

Patients experiencing severe side effects should seek immediate medical attention.

Indications

Vimpat is indicated for:

• Treatment of partial-onset seizures in adults and adolescents aged 4 years and older
• Adjunctive therapy for epilepsy management in patients with refractory partial seizures

Contraindications

Vimpat should not be used in the following situations:

• Patients with known hypersensitivity to Lacosamide or any of the excipients in Vimpat
• Patients with severe cardiac conduction problems, including second or third-degree AV block
• Patients with genetic heart conditions that affect electrical signaling, such as Brugada syndrome

Price in Different Countries

Country	Price (per 60 Tablets)	References
United States	$350	GoodRx Vimpat Price
United Kingdom	£280	NHS Vimpat Price
Canada	$300	Canadian Pharmacy King Vimpat Price
Australia	$320	PBS Vimpat Price
India	₹25,000	1mg Vimpat Price

Top 5 Global Brands

The top five global brands for Lacosamide-based medications include:

• Vimpat (UCB, Inc.): The leading brand known for its efficacy in treating partial-onset seizures with a unique mechanism of action.
• Lacosa (Torrent Pharmaceuticals): Offers a cost-effective alternative for Lacosamide with similar therapeutic benefits.
• Pregabid NT (Intas Pharmaceuticals): A combination medication that includes Lacosamide and is used for epilepsy treatment.
• Lacoset (Sun Pharmaceuticals): Another popular brand offering Lacosamide tablets for seizure management.
• Laft (Micro Labs): Known for its competitive pricing and availability in various markets.