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Yervoy (ipilimumab) is a medication primarily used in the treatment of certain types of cancer, particularly advanced melanoma. It is a monoclonal antibody that targets a protein called cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), which plays a role in regulating the immune response. Mechanism of Action: Yervoy works by blocking the activity of CTLA-4, a protein found on the surface of T cells, which are a type of immune cell. By inhibiting CTLA-4, Yervoy helps to enhance the activation and proliferation of T cells, leading to a stronger immune response against cancer cells. This mechanism helps the immune system recognize and attack cancer cells more effectively. Benefits: The benefits of Yervoy include:
  • Treatment of advanced melanoma, particularly in patients who have not responded to other treatments or have disease progression after initial therapy.
  • Improvement in overall survival and progression-free survival compared to standard treatments in clinical trials.
  • Potential for long-lasting responses and durable remissions in some patients.
Dosage and Administration: Yervoy is administered by intravenous infusion. The recommended dosage and administration schedule may vary depending on factors such as the patient’s weight, medical history, and treatment response. Healthcare professionals typically determine the appropriate dose and infusion schedule. Suitability: Yervoy is indicated for patients with advanced melanoma, particularly those who have not responded to other treatments or have disease progression after initial therapy. Its suitability for an individual patient is determined based on factors such as disease stage, prior treatments received, overall health status, and any underlying medical conditions. Availability and Pricing: Yervoy is available by prescription only and is typically administered in medical facilities equipped to perform intravenous infusions, such as hospitals or specialized clinics. Pricing can vary between countries and regions, and specific pricing information would need to be obtained from pharmaceutical databases, local pharmacies, or healthcare providers. Yervoy represents an important treatment option for individuals with advanced melanoma, offering significant improvement in survival outcomes and the potential for durable responses. However, like all medications, it may cause side effects, and patients should be closely monitored by healthcare professionals during treatment.
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