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  • Zeposia Ozanimod 0.92mg Capsules

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    Description

    Zeposia (Ozanimod) is a prescription medication used primarily for the treatment of certain autoimmune conditions. It is available in the form of 0.92 mg capsules. Zeposia is an oral drug that works by modulating the immune system to reduce inflammation and prevent immune cells from attacking the body’s own tissues. It is used to manage conditions such as multiple sclerosis (MS) and ulcerative colitis (UC).

    How It Works

    Ozanimod, the active ingredient in Zeposia, is a sphingosine-1-phosphate (S1P) receptor modulator. It works by binding to specific receptors on lymphocytes (a type of white blood cell). This binding prevents lymphocytes from exiting the lymph nodes and entering the bloodstream, thereby reducing their ability to migrate to sites of inflammation. As a result, the inflammatory response is diminished, which helps manage conditions like MS and UC.

    Side Effects

    Common side effects of Zeposia include:
    • Headache
    • Fatigue
    • Nausea
    • Diarrhea
    • Back pain
    • Elevated liver enzymes
    Serious side effects may include:
    • Bradycardia (slow heart rate)
    • Infections (due to immunosuppression)
    • Hepatotoxicity (liver damage)
    • Macular edema (swelling in the retina)
    • Hypertension (high blood pressure)
    Patients should contact their healthcare provider if they experience any severe or unusual symptoms.

    Indications

    Zeposia is indicated for:
    • Treatment of adults with relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.
    • Treatment of adults with moderately to severely active ulcerative colitis who have had an inadequate response or intolerance to other therapies.

    Contraindications

    Zeposia should not be used in patients with:
    • Known hypersensitivity to ozanimod or any of the excipients in the formulation.
    • Severe hepatic impairment or active liver disease.
    • Pregnancy and breastfeeding, unless the potential benefits outweigh the risks, as the safety of Zeposia during these periods has not been established.
    • Patients with a history of serious heart rhythm issues or bradycardia without appropriate cardiac monitoring.

    Price in Different Countries

    Country Price (per 0.92 mg Capsule) References
    United States $7,500 – $8,500 per month GoodRx Zeposia Price
    United Kingdom £5,000 – £6,000 per month NHS Zeposia Price
    Australia $10,000 AUD per month PBS Zeposia Price
    India ₹60,000 – ₹70,000 per month 1mg Zeposia Price
    Canada $8,000 – $9,000 CAD per month Canadian Pharmacy Zeposia Price

    Top 5 Global Brands

    For managing autoimmune conditions and other similar treatments, the top global brands include:
    • Ocrevus (Ocrelizumab) – Genentech: A monoclonal antibody used to treat multiple sclerosis.
    • Copaxone (Glatiramer Acetate) – Teva Pharmaceuticals: Used for treating multiple sclerosis.
    • Tysabri (Natalizumab) – Biogen: A monoclonal antibody for multiple sclerosis treatment.
    • Humira (Adalimumab) – AbbVie: Used for various autoimmune conditions like rheumatoid arthritis and Crohn’s disease.
    • Enbrel (Etanercept) – Amgen: A biologic used to treat autoimmune diseases such as rheumatoid arthritis and psoriasis.
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