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  • Lamivudine

    Lamivudine is an antiviral medication that can be used to treat HIV/AIDS and chronic hepatitis B infections. It belongs to a class of drugs called nucleoside reverse transcriptase inhibitors (NRTIs), which work by blocking the viral enzyme that copies the viral genetic material. Lamivudine is effective against both HIV-1 and HIV-2, but it is not a cure for either infection. Lamivudine is usually taken in combination with other antiretroviral drugs to prevent the development of drug resistance.

    Lamivudine for Exporters in UAE

    If you are an exporter based in UAE and want to export lamivudine to the world market, you need to know some important information about this drug, such as its indications, dosage, side effects, interactions, and prices in different countries. Here are some key points to consider:

    • Lamivudine is approved by the US Food and Drug Administration (FDA), the European Medicines Agency (EMA), and the World Health Organization (WHO) for the treatment of HIV/AIDS and chronic hepatitis B infections.
    • Lamivudine is available in different formulations, such as tablets, oral solution, and injectable solution. The most common strengths are 100 mg, 150 mg, and 300 mg for tablets, and 10 mg/mL and 5 mg/mL for oral solution.
    • The recommended dosage of lamivudine for adults with HIV/AIDS is 300 mg once daily or 150 mg twice daily, in combination with other antiretroviral drugs. The recommended dosage for children with HIV/AIDS is based on their body weight and age, ranging from 4 mg/kg twice daily to 150 mg twice daily.
    • The recommended dosage of lamivudine for adults with chronic hepatitis B is 100 mg once daily. The recommended dosage for children with chronic hepatitis B is based on their body weight, ranging from 0.5 mg/kg to 3 mg/kg once daily.
    • Lamivudine can cause some common side effects, such as nausea, diarrhea, headache, fatigue, and cough. It can also cause some serious side effects, such as liver damage, lactic acidosis, pancreatitis, and worsening of hepatitis B after stopping treatment.
    • Lamivudine can interact with some other drugs, such as trimethoprim/sulfamethoxazole, ribavirin, ganciclovir, interferon alfa, and other NRTIs. These interactions can increase or decrease the levels of lamivudine or the other drugs in the blood, which may affect their effectiveness or safety.
    • The price of lamivudine varies depending on the country, the supplier, the formulation, and the strength. The following table shows some examples of the prices of lamivudine in different countries as of October 2023.

    Top 5 Global Brands of Lamivudine

    Lamivudine is marketed under different brand names by different pharmaceutical companies around the world. Some of the most popular and widely used brands are:

    1. Epivir: This is the original brand name of lamivudine, developed by GlaxoSmithKline. It is available in tablets and oral solution for the treatment of HIV/AIDS and chronic hepatitis B.
    2. Epivir-HBV: This is a lower-dose version of Epivir, specifically designed for the treatment of chronic hepatitis B. It is available in tablets and oral solution.
    3. Combivir: This is a fixed-dose combination of lamivudine and zidovudine, another NRTI. It is available in tablets for the treatment of HIV/AIDS.
    4. Triumeq: This is a fixed-dose combination of lamivudine, abacavir, and dolutegravir, another NRTI and an integrase inhibitor. It is available in tablets for the treatment of HIV/AIDS.
    5. Heptodin: This is a generic brand name of lamivudine, manufactured by Cipla. It is available in tablets and oral solution for the treatment of HIV/AIDS and chronic hepatitis B.

    Lamivudine is a valuable antiviral drug that can help many people with HIV/AIDS and chronic hepatitis B infections. However, it is not a cure and it requires careful monitoring and adherence to the prescribed regimen. If you are an exporter of lamivudine, you should be aware of the indications, dosage, side effects, interactions, and prices of this drug in different countries and markets. You should also be familiar with the top global brands of lamivudine and their features.

    : https://en.wikipedia.org/wiki/Lamivudine
    : https://www.drugs.com/mtm/lamivudine.html
    : https://medlineplus.gov/druginfo/meds/a696011.html
    : https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020564s038lbl.pdf
    : https://www.goodrx.com/lamivudine
    : https://bnf.nice.org.uk/drug/lamivudine.html
    : https://www.medguideindia.com/show_brand.php?nav_link=&pageNum_rr=0&nav_link=&selectme=0&brandid=1008
    : http://www.chinaphar.com/article/view/10067
    : http://portal.anvisa.gov.br/documents/33836/2568070/RE_1_2015_.pdf/f46585a3-3d14-4a6b-8c1b-fe650a0c701e
    : https://www.drugs.com/mtm/lamivudine-and-zidovudine.html
    : https://www.drugs.com/triumeq.html
    : https://www.cipla.com/sites/default/files/2019-08/Cipla%20AR%202018-19.pdf

    CountryFormulationStrengthPrice per UnitReference
    USATablet300 mg$0.67[5]
    UKTablet150 mg$0.24[6]
    IndiaTablet150 mg$0.04[7]
    ChinaOral Solution10 mg/mL$0.03 per mL[8]
    BrazilInjectable Solution10 mg/mL$0.12 per mL[9]

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