Aranesp 150 mcg ( Darbepoetin ) Pre-Filled Syringe

How It Works

Aranesp (Darbepoetin alfa) is a synthetic form of erythropoietin, a protein that stimulates the production of red blood cells. It is used to treat anemia, particularly in patients with chronic kidney disease (CKD) or those undergoing chemotherapy. Darbepoetin alfa works by binding to the erythropoietin receptor on erythroid progenitor cells in the bone marrow, promoting their survival, proliferation, and differentiation into mature red blood cells. This helps to increase the red blood cell count and improve the oxygen-carrying capacity of the blood, alleviating symptoms of anemia.

List of Side Effects

• Hypertension (high blood pressure)
• Edema (swelling)
• Thromboembolic events (blood clots)
• Fatigue
• Dyspnea (shortness of breath)
• Injection site reactions
• Rash
• Headache
• Nausea
• Myalgia (muscle pain)
• Diarrhea

List of Indications

• Anemia associated with chronic kidney disease (CKD) in adult and pediatric patients
• Anemia due to concomitant myelosuppressive chemotherapy in patients with non-myeloid malignancies

List of Contraindications

• Uncontrolled hypertension
• Pure red cell aplasia (PRCA) that begins after treatment with Aranesp or other erythropoiesis-stimulating agents (ESAs)
• Hypersensitivity to darbepoetin alfa or any of its excipients

Price in Different Countries

Country	Price (USD)	Reference Website
United States	$1,000	GoodRx
United Kingdom	?800	NICE BNF
Canada	$1,200 CAD	CanadaDrugs.com
Australia	$1,400 AUD	PBS Australia
India	?60,000 INR	1mg
Pakistan	? 200,000 PKR	Dawaai.pk

Top 5 Global Brands

1. Aranesp (Darbepoetin alfa) – Amgen
2. Epogen (Epoetin alfa) – Amgen
3. Procrit (Epoetin alfa) – Janssen
4. Neorecormon (Epoetin beta) – Roche
5. Retacrit (Epoetin alfa-epbx) – Pfizer