Juluca 50 mg/25 mg film-coated tablets


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How Juluca Works

Juluca is a medication used in the treatment of HIV-1 infection in adults who have achieved viral suppression. It contains two active ingredients: dolutegravir and rilpivirine. Dolutegravir belongs to a class of drugs called integrase inhibitors, which work by blocking the action of an enzyme called integrase, preventing the integration of HIV DNA into the DNA of human immune cells. Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that inhibits the reverse transcriptase enzyme, thereby preventing the conversion of HIV RNA into DNA. By inhibiting these enzymes, Juluca helps to reduce the amount of HIV in the body and maintain viral suppression.

Side Effects of Juluca

  • Headache
  • Nausea
  • Dizziness
  • Fatigue
  • Insomnia
  • Abdominal pain
  • Rash
  • Diarrhea
  • Depression
These side effects may vary in severity and may require medical attention depending on individual circumstances.

Indications for Juluca

  • Treatment of HIV-1 infection in adults who have achieved viral suppression

Contraindications for Juluca

  • Hypersensitivity to dolutegravir, rilpivirine, or any component of the formulation
  • Co-administration with dofetilide, carbamazepine, oxcarbazepine, phenytoin, phenobarbital, or rifampin
  • Pregnancy or breastfeeding
  • Severe liver impairment

Price Comparison of Emgality in Different Countries

Country Price (per injection) Reference
Pakistan PKR 15,000 medicalstore.com.pk Pakistan
United States USD 1,200 ViiV Healthcare US
United Kingdom GBP 900 ViiV Healthcare UK
Canada CAD 1,500 ViiV Healthcare Canada
Australia AUD 1,800 ViiV Healthcare Australia

Top 5 Global Brands of HIV Medications

  1. Truvada (Emtricitabine/Tenofovir)
  2. Atripla (Efavirenz/Emtricitabine/Tenofovir)
  3. Prezista (Darunavir)
  4. Isentress (Raltegravir)
  5. Juluca (Dolutegravir/Rilpivirine)
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