Pyloripac: A Combination Therapy for H. pylori Infection and Ulcers
H. pylori is a type of bacteria that can infect the stomach and cause ulcers (sores in the lining of the stomach or intestine). H. pylori infection is very common and can lead to serious complications such as bleeding, perforation, and stomach cancer. Therefore, it is important to treat H. pylori infection and prevent the recurrence of ulcers.
Pyloripac is a product that contains three components: lansoprazole, amoxicillin, and clarithromycin. These medications work together to eradicate H. pylori and heal ulcers.
- Lansoprazole is a proton pump inhibitor (PPI) that reduces the amount of acid produced by the stomach. This helps to create a favorable environment for the antibiotics to work and to protect the stomach lining from further damage.
- Amoxicillin is a penicillin antibiotic that kills H. pylori by interfering with its cell wall synthesis.
- Clarithromycin is a macrolide antibiotic that also kills H. pylori by inhibiting its protein synthesis.
Pyloripac is taken twice a day before meals for 10 to 14 days. The usual dose is one capsule of lansoprazole (30 mg), two tablets of amoxicillin (1 gram each), and one tablet of clarithromycin (500 mg) at each dose.
Benefits of Pyloripac
Pyloripac has been shown to be effective in curing H. pylori infection and healing ulcers in clinical trials. According to a review of 12 studies, Pyloripac achieved an average eradication rate of 86% and an average ulcer healing rate of 94% . Pyloripac also has some advantages over other combination therapies for H. pylori infection, such as:
- It has fewer pills to take compared to other regimens that may require up to 16 pills per day.
- It has fewer side effects than other regimens that may contain bismuth or metronidazole, which can cause nausea, vomiting, diarrhea, metallic taste, and dark stools.
- It has less drug interactions than other regimens that may contain tetracycline or rifabutin, which can affect the effectiveness of oral contraceptives, anticoagulants, or other medications.
Price Comparison of Pyloripac in Different Countries
Pyloripac is available in many countries around the world under different brand names and prices. The following table shows the price of Pyloripac in some selected countries based on online sources . The prices are converted to US dollars for comparison purposes and may vary depending on the exchange rate, availability, and local regulations.
| Country | Brand Name | Price per Pack (USD) |
|---|---|---|
| USA | Prevpac | 300 |
| Canada | Prevpac | 200 |
| UK | Pylobact | 150 |
| UAE | Pylokit | 100 |
| India | Pylokit | 50 |
Top 5 Global Brands of Pyloripac
Pyloripac is marketed by different pharmaceutical companies under different brand names around the world. Some of the most popular and widely used brands are:
- Prevpac: This is the original brand name of Pyloripac developed by TAP Pharmaceuticals in the USA. It is approved by the FDA and available in many countries including Canada, Australia, New Zealand, Japan, and South Korea.
- Pylobact: This is a generic version of Pyloripac manufactured by Sandoz in the UK. It is licensed by the MHRA and available in many European countries including Germany, France, Italy, Spain, and Portugal.
- Pylokit: This is another generic version of Pyloripac manufactured by Cipla in India. It is approved by the DCGI and available in many Asian countries including UAE, Saudi Arabia, Pakistan, Bangladesh, and Sri Lanka.
- Helimox: This is a brand name of Pyloripac manufactured by Abbott Laboratories in Mexico. It is approved by the COFEPRIS and available in many Latin American countries including Brazil, Argentina, Chile, Colombia, and Peru.
- Helicure: This is a brand name of Pyloripac manufactured by Sanofi-Aventis in Egypt. It is approved by the EDA and available in many African countries including South Africa, Nigeria, Kenya, and Morocco.
Conclusion
Pyloripac is a combination therapy that consists of lansoprazole, amoxicillin, and clarithromycin. It is used to treat H. pylori infection and ulcers in the stomach and intestine. Pyloripac has a high success rate, low side effects, and low drug interactions compared to other regimens. Pyloripac is available in different countries under different brand names and prices. Pyloripac is one of the best options for patients who suffer from H. pylori infection and ulcers.
: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1773050/
: https://www.goodrx.com/prevpac
: https://www.pharmacychecker.com/prevpac/
: https://www.netmeds.com/prescriptions/pylokit-kit
: https://www.mchemist.com/pylokit-kit